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Repigmentation of Gray Hair in Lesions of Annular Elastolytic Giant Cell Granuloma

Cutis. 2015 July;96(1):E19-E22
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Hair pigmentation is a complex phenomenon that involves many hormones, neurotransmitters, cytokines, growth factors, eicosanoids, cyclic nucleotides, nutrients, and a physicochemical milieu. We report a case of repigmentation of gray hairs in lesions of annular elastolytic giant cell granuloma (AEGCG) on the scalp of a 67-year-old man.

   Practice Points

 

  • Hair repigmentation can be a clinical clue to a subjacent inflammatory disease.
  • Hair depigmentation associated with aging may be a reversible condition under proper stimulation.

Figure 5. A hair bulb of a normal follicle showing the morphology of melanocytes, which are dendritic and large (H&E,original magnification ×100).