Blue-black hyperpigmentation on the extremities
The Journal of Family Practice. 2022 December;71(10):445-447 | doi: 10.12788/jfp.0520
December 19, 2022|Family Medicine
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In some cases, diagnosis entails less “what is it?” and more “what caused it?”
A 68-year-old man with type 2 diabetes presented with progressive hyperpigmentation of the lower extremities and face over the past 3 years. Clinical examination revealed confluent, blue-black hyperpigmentation of the lower extremities (Figure), upper extremities, neck, and face. Laboratory tests and arterial studies were within normal ranges. The patient’s medication list included lisinopril 10 mg/d, metformin 1000 mg twice daily, minocycline 100 mg twice daily, and omeprazole 20 mg/d.
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