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Triplet appears safe, effective for gynecologic cancers
HONOLULU – Tumor response rate was 40% with pembrolizumab plus bevacizumab and oral metronomic cyclophosphamide in patients with recurrent...
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Combo may improve PFS, OS for certain ovarian cancer patients
HONOLULU - Combining avelumab with pegylated liposomal doxorubicin may provide a survival benefit in certain patients with platinum-resistant or...
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Financial toxicity may be common in gynecologic cancer patients
HONOLULU – A small survey suggests financial toxicity may be common among gynecologic cancer patients starting a new line of treatment.
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Financial assistance programs may speed treatment for cervical cancer
HONOLULU – Financial assistance programs may help lower-income cervical cancer patients complete treatment in a...
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Brachytherapy proves beneficial regardless of treatment duration
HONOLULU – The median overall survival was better among patients who received brachytherapy for 8 weeks or longer...
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Oral triplet deemed effective in relapsed/refractory myeloma
Combination clarithromycin, pomalidomide, and dexamethasone may be a treatment option for patients with relapsed or refractory multiple myeloma....
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Guadecitabine may be option for certain MDS/AML patients
Patients with few or no somatic mutations were more likely to respond to guadecitabine in the phase 2 trial.
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Early career researchers win funding
Seven researchers won funding from the Parker Institute for Cancer Immunotherapy, and another researcher received a grant from the Ovarian Cancer...
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Analysis suggests ‘Burkitt-like lymphoma’ is a misnomer
Burkitt-like lymphoma with 11q aberration appears more closely related to other lymphomas than to typical Burkitt lymphoma.
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KD025 produces durable responses in patients with cGVHD
HOUSTON – Many responses have lasted 20 weeks or more, and durability data are still maturing.
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Ixazomib targets treatment failure in chronic GVHD
HOUSTON – Most patients in the phase 2 trial had severe chronic graft-versus-host disease and most had received three or more prior lines of...
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Post-HCT azithromycin doesn’t increase relapse risk, study suggests
HOUSTON – A prior study indicated that pretransplant azithromycin increases the risk of relapse.
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Gene expression signature reveals high-grade GCB DLBCL
Patients with this signature had inferior survival outcomes.
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Priority review granted to lenalidomide for FL, MZL
Celgene is seeking approval for lenalidomide in combination with rituximab to treat previously treated follicular lymphoma or marginal zone...
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FDA approves subcutaneous trastuzumab for HER2-positive breast cancers
The subcutaneous formulation of trastuzumab can be administered over approximately 2-5 minutes.