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CAR T-cell therapy less effective in transformed follicular lymphoma
The complete response rate and duration of response were better in patients with follicular lymphoma than in those with transformed follicular...
News
Guidelines update donor selection criteria for HSCT
The evidence-based guidelines provide recommendations for selecting adult donors and cord blood units for allogeneic hematopoietic stem cell...
News
Large genetic cohort supports NfL as Alzheimer’s biomarker
LOS ANGELES – Mutation carriers in the world’s largest early onset AD cohort saw significant increases in neurofilament light (NfL) from age 22...
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Test could inform care of patients with pancreatic cysts
The test, CompCyst, correctly identified 91% of patients who required surgery, 49% of those who required monitoring, and 60% of patients who...
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Investigators target brain metastases in NSCLC
In a retrospective study of matched primary and metastases samples, PI3K signaling was associated with an increased risk of brain metastases, and...
Article
Endoscopic treatment effective in T1b esophageal cancer
A systematic review suggests endoscopic treatment is appropriate for T1b esophageal cancers with a low risk of metastasis.
Article
New appointments at City of Hope, UA, and Fox Chase
The University of Arizona (UA) Cancer Center has a new interim director, two hematologists have earned new positions at City of Hope, and an...
Article
Endoscopic treatment effective in T1b esophageal cancer
A systematic review suggests endoscopic treatment is appropriate for T1b esophageal cancers with a low risk of metastasis.
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SC daratumumab deemed feasible for every multiple myeloma patient
CHICAGO – In the COLUMBA trial, subcutaneous daratumumab proved noninferior to intravenous daratumumab in overall response rate and maximum trough...
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CNS-directed therapy appears more effective for synDLBCL
Two-year survival rates were superior among patients who received CNS-intensive therapy.
Article
Hemostasis researcher passes away at age 72
Dr. George J. Broze, who is known for his research on hemostasis and the relationship between coagulation and inflammation, died following a heart...
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‘Robust antitumor immune responses’ observed in pediatric ALL
Tumor-associated CD8+ T cells responded to 86% of neoantigens tested and recognized 68% of neoepitopes tested in samples from pediatric ALL...
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BET inhibitors may target oncogene in ABC-like DLBCL
Preclinical research suggests TCF4 is an oncogene in ABC-like DLBCL and can be targeted via BET inhibition.
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‘Encouraging’ responses seen with durvalumab plus R-CHOP in DLBCL
CHICAGO – Durvalumab plus R-CHOP induction produced a complete response rate of 54%.
Article
Stand Up To Cancer adds research muscle
Dr. John D. Carpten and Dr. Roderic I. Pettigrew have joined the Stand Up To Cancer scientific advisory committee. And Fox Chase Cancer Center in...