Brian F. Mandell, MD, PhD

Article

Kidneys have a lot of nerve

Author:: Brian F. Mandell, MD, PhD

Publish date: July 1, 2012

Renal denervation shows promise. But hypertension is a heterogeneous condition, and the patient's underlying pathophysiology may dictate the respon...

Article

Fire, skin, and fat: Inflammation, psoriasis, and cardiovascular disease

Author:: Brian F. Mandell, MD, PhD

Publish date: June 1, 2012

The connection between psoriasis and atherosclerosis is not well understood, but we should be vigilant about cardiovascular risk factors in these p...

Article

Lung cancer screening: One step forward

Author:: Brian F. Mandell, MD, PhD

Publish date: May 1, 2012

I never expected, perhaps naively, that cancer screening would be so challenging and contentious.

Article

Examine before ordering: An algorithm unchanged by new tests

Author:: Brian F. Mandell, MD, PhD

Publish date: April 1, 2012

I have always been irked when doctors reflexively order panels of immunologic tests when evaluating patients with "arthritis."

Article

Exploring the human genome, and relearning genetics by necessity

Author:: Brian F. Mandell, MD, PhD

Publish date: March 1, 2012

The field of medical genetics continues to advance far beyond what many of us were exposed to in medical school.

Article

Talking to patients: Barriers to overcome

Author:: Brian F. Mandell, MD, PhD

Publish date: February 1, 2012

Not all patients think like doctors, but we need to be able to think like patients.

Article

Bugs, pundits, evolution, and the New Year

Author:: Brian F. Mandell, MD, PhD

Publish date: January 1, 2012

Pathogens continue to evolve, influenced by human behavior but untouched by partisan dialogue and undaunted by doubting politicians.

Article

Quality, frailty, and common sense

Author:: Brian F. Mandell, MD, PhD

Publish date: December 1, 2011

Ideal management of a frail older person with severe congestive heart failure is not always about devices and drugs.

Article

The bittersweet of steroid therapy

Author:: Brian F. Mandell, MD, PhD

Publish date: November 1, 2011

Every physician has had patients with the long-term effects of glucocorticoid therapy, including diabetes.

Article

A discussion of dissection

Author:: Brian F. Mandell, MD, PhD

Publish date: October 1, 2011

Few medical emergencies are as dramatic as an acutely rupturing aortic aneurysm. Advances in research offer potential for more alternatives to emer...

Article

When to stop treating the bones

Author:: Brian F. Mandell, MD, PhD

Publish date: September 1, 2011

Don't let the argument about how long to treat osteoporosis with bisphosphonate drugs stand in the way of initiating therapy in patients at risk of...

Article

Out of Morpheus’ embrace

Author:: Brian F. Mandell, MD, PhD

Publish date: August 1, 2011

We still lack a full understanding of the complex physiology of sleep and the effects of sleep deprivation on a number of clinical conditions, from...

Article

When good drugs turn weirdly bad

Author:: Brian F. Mandell, MD, PhD

Publish date: July 1, 2011

Even the most specific of drugs, such as interferon, can have untoward biologic effects.

Article

The pain of cholesterol-lowering therapy

Author:: Brian F. Mandell, MD, PhD

Publish date: June 1, 2011

It seems that everyone "knows" that statins cause muscle pain, including many patients with hypercholesterolemia.

Article

Recognizing the unusual: The diagnostic epiphany

Author:: Brian F. Mandell, MD, PhD

Publish date: May 1, 2011

We have all experienced the sudden recognition of an unexpected diagnosis, such as the case of visceral angioedema due to angiotensin-converting en...