Kids and clots: Expecting the unexpected

"Neither low-molecular-weight nor unfractionated heparin should ever be used in children with heparin-induced thrombocytopenia," Dr. Callahan said. "In this setting, one of the newer anticoagulants, such as direct thrombin or selective Xa inhibitors, should be used."

About 10% of children with a clot will die, but mortality is highly associated with underlying disease. Children who do survive have a risk of recurrence and an increased risk of death with each recurrence.

Dr. Callahan had no financial disclosures.

msullivan@frontlinemedcom.com