Clinical Edge

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Breastfeeding and Endometrial Cancer Risk

Obstet Gynecol; ePub 2017 May 5; Jordan, et al

Women who breastfeed have a reduced endometrial cancer risk, a recent study found. The meta-analysis included data from 3 cohorts and 14 case-control studies and examined the association between breastfeeding and endometrial cancer risk. After excluding nulliparous women, the analyses included 8,981 women with endometrial cancer and 17,241 women in a control group. Researchers found:

  • Ever breastfeeding was associated with an 11% reduction in risk of endometrial cancer.
  • Longer average duration of breastfeeding per child was associated with lower risk of endometrial cancer; however, there was a leveling of this effect beyond 6-9 months.
  • The association with ever breastfeeding did not vary notably by body mass index or histologic subtype.


Jordan SJ, Na R, Johnatty SE, et al. Breastfeeding and endometrial cancer risk: An analysis from the Epidemiology of Endometrial Cancer Consortium. [Published online ahead of print May 5, 2017]. Obstet Gynecol. doi:10.1097/AOG.0000000000002057.