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Cost-Effectiveness of Genetic Screening for Lynch Syndrome

Supported by Myriad Genetics Laboratories, Inc.
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Is risk-assessment-based population screening for Lynch syndrome a clinically beneficial and cost-effective strategy for improving health outcomes? A recent study by Dinh and colleagues showed that such screening could be economically feasible.1 Because there is a strong link between Lynch syndrome and a woman’s risk of developing cancer, and because clinically relevant genetic testing for Lynch syndrome is widely available, this recent study may show that screening the general population followed by testing for gene mutations associated with Lynch syndrome may be an important and cost-effective measure to reduce the morbidity and mortality associated with the development of certain malignancies in women.1 If such screening is associated with our patients’ long-term health, ObGyns should better understand this syndrome and consider the details of this study.

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