Key clinical point: The presence of uterine fibroids in early pregnancy is significantly and independently associated with higher odds of developing preeclampsia in the middle and late trimesters.
Major finding: Pregnant women with vs without uterine fibroids in early pregnancy had a 3-fold higher risk for preeclampsia (adjusted odds ratio 3.02; P = .019).
Study details: This case-control study included 121 pregnant women diagnosed with preeclampsia and 578 age-matched pregnant women without preeclampsia.
Disclosures: This study did not report the funding source. The authors declared no conflicts of interest.
Source: Gong L et al. Uterine fibroids are associated with increased risk of pre-eclampsia: A case-control study. Front Cardiovasc Med. 2022;9:1011311 (Oct 18). Doi: 10.3389/fcvm.2022.1011311