Medical Education Library

Neuromyelitis Optica Spectrum Disorders:
Critical Role of Complement-Dependent Cytotoxicity


This supplement is sponsored by Alexion Pharmaceuticals, Inc.

The complement system was once thought to have a fairly lim­ited role in the immune system, recognizing and eliminating pathogens. Now, however, complement proteins are known to have a much broader role in immunity, and dysregulation of the complement system has been shown to affect the patho­genesis and clinical picture of several autoimmune diseases. This supplement discusses the role of complement-dependent cytotoxicity in the pathophysiology of neuromyelitis optica spectrum disorders.

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