The Effect of an Inpatient Smoking Cessation Treatment Program on Hospital Readmissions and Length of Stay
BACKGROUND: Most clinical research involving tobacco dependence treatment is related to outpatient interventions and focuses on health outcomes. Inpatient smoking cessation treatment has been found to be cost-effective in the Canadian healthcare system, but the finding’s applicability to US health systems is unclear.
OBJECTIVE: The objective of this study is to estimate the impact of an inpatient tobacco cessation treatment program on 30-day readmission rates and length of stay (LOS).
METHODS: Participants were 28,994 patients admitted to the hospital between July 2012 and July 2014. Smokers were identified through the electronic medical records system and were offered cessation treatment. Program effects were estimated by using a difference-in-differences approach, comparing all smokers to all nonsmokers before versus after introduction of the program. Readmission rates were modeled by using probit regression; LOS was modeled by using truncated negative binomial regression. Models controlled for age, sex, race, payer, hospital department, severity of illness, and intensive care unit days.
RESULTS: The hospital-initiated smoking cessation intervention had no significant effect on 30-day readmission rates or LOS. Other control variables had the expected signs and were statistically significant.
CONCLUSIONS: The evaluation of an inpatient tobacco dependence treatment did not find significant short-term changes in healthcare utilization in the first 30 days after initial hospitalization.
© 2017 Society of Hospital Medicine
DISCUSSION
This study investigated the effect of an inpatient smoking cessation program, based on a successful Canadian model, on inpatient readmission rates and LOS. The program showed no effect on 30-day readmission rates or LOS. We see several potential explanations for the absence of a detectable impact.
First, the ITT approach reflected real-world implementation of smoking cessation services. The ITT approach adopts the hospital’s perspective because the hospital will assess overall effectiveness without regard to programmatic limitations. The intervention group for this analysis included individuals who were offered but declined treatment, individuals who accepted treatment but failed to quit smoking, and individuals who both accepted treatment and quit smoking. If the analysis had focused only on the latter group, an effect would have been more likely to be found. Further analysis of the subset of patients who accepted the intervention and quit smoking is warranted. Nevertheless, hospitals cannot expect all inpatient smokers, or even a majority, to embrace an offer of cessation treatment. This also emphasizes the challenges hospitals will face in offering tobacco cessation programs to smokers in a timely way. Reasons for patients not receiving orders varied but included issues with weekend admissions.
Second, the timeframe of the analysis is limited to the inpatient stay (for LOS) and 30 days (for readmission). A longer-term analysis might have found an effect. However, we examined this from the hospital perspective. For the hospital, LOS is a key cost driver; thus, reductions in LOS would create a strong financial incentive for hospitals to implement smoking cessation programs. Similarly, reducing readmissions is now a priority for hospitals because of new Medicare rules that penalize hospitals for readmissions. Thus, the 2 outcomes we examined are outcomes that are financially important to hospitals.
There are several limitations to our analysis. First, the difference-in-differences model assumes that in the absence of treatment, the average change in the dependent variables would have been the same for both the treatment and control groups, also known as the parallel trends assumption. Specification tests showed this assumption was met for the preperiod. Second, our study relies on electronic health record data to identify smokers. However, 93% of individuals who were identified as smokers confirmed their smoking status upon interview. Finally, we looked at all categories of inpatient admissions. Improvement in LOS and short-term readmission rates may be limited to patients admitted for specific conditions, such as cardiovascular and respiratory conditions.
There are a number of plausible reasons for our null finding. First, the “dose” of intervention may have been too weak; that is, the number of smokers who were offered the treatment, accepted the treatment, and adhered to the treatment may have been too low, leading to too few smokers quitting smoking and, thus, no effect of the intervention on our outcomes. This follows directly from the ITT design of the study.23 This suggests that hospitals who wish to adopt smoking cessation programs need to focus on ensuring a timely offering of treatment and encouragement of uptake by smokers.
A second reason for the null finding may have been the short duration for the NRT, which was only offered for 2 weeks. Research suggests that use of NRT for less than 4 weeks is associated with a reduced likelihood of smoking cessation.24 However, a review of the literature concludes that the duration of NRT is less important than the dosage and the combination of NRT with other forms of smoking cessation therapy.25 It is important to note that this study used NRT; other treatments such as Chantix could have different effectiveness.26,27 Further research on different treatment approaches, including longer duration of NRT, would be appropriate.
Disclosure
The authors have no competing interests or conflicts to report. The study was supported by contract number 15FLA68717 from the Colorado Department of Public Health and Environment.