TOMM40 Gene Varient May Enable Early AD Treatment

He stressed that none of the subjects in either the brain volume study or the memory study had any observable memory difficulties in their everyday life. “But these findings of gray matter loss and cognitive changes in these relatively young people are very important,” and suggest that “we may have the ability to find people at risk of Alzheimer's very early on in the disease process, far in advance of any significant cognitive problems.”

Patients with short TOMM40 had greater gray matter volume that did those with two very long versions.

Source Courtesy Dr. Sterling Johnson