Clinical Edge Journal Scan

Candida albicans exhibits high exoenzyme activity in diabetes patients


Key clinical point: Candida albicans showed the strongest exoenzyme activity compared to non-albicans isolates in oral cavity samples from adults with diabetes.

Major finding: Candida albicans isolates showed 97.3%, 100%, and 77.3% exoenzyme activity for phospholipase, hemolysin, and esterase, respectively. Differences in activity between albicans and non- albicans isolates were significant for phospholipase and hemolysin, but did not reach significance for esterase.

Study details: The data come from 108 Candida species including 75 Candida albicans and 33 non- albicans taken from diabetes patients’ oral cavity samples.

Disclosures: The study was supported by the Deputy of Research and Technology of Shiraz University of Medical Sciences, Shiraz, Iran. The study was part of the MD thesis of coauthor Mehdi Ghaderian Jahromi. The researchers had no financial conflicts to disclose.

Source: Nouraei H et al. Biomed Res Int. 2021 May 26. doi: 10.1155/2021/9982744.

Recommended Reading

Posaconazole posts strong results against invasive fungal infections in cancer patients
MDedge Infectious Disease
Coinfections raise mortality rates in COVID-19 patients
MDedge Infectious Disease
Diagnostic tests may miss invasive aspergillosis in children
MDedge Infectious Disease
Watch for mucormycosis in COVID-19 patients
MDedge Infectious Disease
Serious infections arise in pediatric transplant patients
MDedge Infectious Disease