If you work on the front lines of medical care, treating patients with hepatitis, you may not have time to review all the hepatitis research that enters the medical literature every month. Here’s a quick look at some notable news items and journal articles published over the past month, covering the major hepatitis viruses.
Preliver transplant treatment withprovides the best health outcomes and is the most cost-effective strategy for the treatment of patients with hepatitis C virus with hepatocellular carcinoma or decompensated cirrhosis who are waitlisted for liver transplant, a study in Hepatology revealed.
A recent study in the Journal of Viral Hepatitis found that patients with chronic HCV and compensated or decompensated cirrhosis who achieve sustained viral responsein hepatic venous pressure gradient at long-term follow-up.
The hepatic expressions of cannabinoid receptor 1 and cannabinoid receptor 2 playinduced by chronic hepatitis B virus, according to a study in the International Journal of Infectious Diseases.
A study in the Journal of Viral Hepatitis found that the Pooled Cohort atherosclerotic cardiovascular disease risk equationamong lower-risk patients and underestimated risk among higher-risk patients in both HCV-infected and uninfected groups.
A multinational study in Hepatology found thatwere similar in patients with inherited bleeding disorders and HCV infection who received elbasvir/grazoprevir and placebo.
The number of HBV patients in the United Statesremained stable, according to a recent study in the Journal of Viral Hepatitis, but the proportion of HBV patients with hepatocellular carcinoma continues to rise.
A research letter in the Morbidity and Mortality Weekly Report reportedfrom the inappropriate reuse of saline flush syringes for multiple patients in an acute care hospital in Texas.
A large German study in the Journal of Viral Hepatitis found that ombitasvir/paritaprevir/ritonavir plus/minus dasabuvir plus/minus ribavirin for treatment of HCV genotype 1 and genotype 4 infectionin clinical practice.
A study, conducted in South Korea, in Hepatology found that monotherapy with tenofovir disoproxil fumarate wasin heavily pretreated patients with multidrug-resistant HBV infection.
Overt and occult HBV infection of children was more serious in underdeveloped northwest regions of China, a study in the Journal of Viral Hepatitis found, suggesting thatshould be strengthened and supplemented.
A study in Hepatology found that long-term entecavir monotherapy isafter liver transplantation for chronic HBV, with a durable HBV surface antigen seroclearance rate of 92%, undetectable HBV DNA rate of 100% at 8 years, and excellent long-term survival of 85% at 9 years.
An Italian study in the Journal of Viral Hepatitis found that treatment with direct-acting antivirals was, although cirrhotic subjects with Model For End-Stage Liver Disease scores greater than 10 and albumin levels below 3 g/dL showed a higher risk of developing serious adverse events and treatment failure.
Direct-acting antiviral–based treatments for severe posttransplant HCV recurrence, comprising fibrosing cholestatic hepatitis,even without viral clearance and permits excellent long-term survival, according to a study in the Journal of Viral Hepatitis.