Radiopharmaceuticals: Present and Future
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In cancer patients, bone metastasis is a common complication, with the highest prevalence among breast and prostate cancer patients. Pain is one of the most feared and debilitating cancer-related symptoms, with an incidence of 62%–86%. Pain related to bone metastases constitutes the most frequent type of pain. The objectives of treating bone metastases are to palliate pain, improve quality of life, prolong pain-free survival, and eradicate tumor cells in the bone. Traditional treatment approaches include external beam radiation, orthopedic intervention, chemotherapy, hormone therapy, bisphosphonates, steroids, and radiopharmaceuticals.