The Use of Valeriana officinalis (Valerian) in Improving Sleep in Patients Who Are Undergoing Treatment for Cancer: A Phase III Randomized, Placebo-Controlled, Double-Blind Study (NCCTG Trial, N01C5)
February 13, 2011|Hematology and Oncology
Author and Disclosure Information
Sleep disorders are a substantial problem for cancer survivors, with prevalence estimates ranging from 23% to 61%. Although numerous prescription hypnotics are available, few are approved for long-term use or have demonstrated benefit in this circumstance. Hypnotics may have unwanted side effects and are costly, and cancer survivors often wish to avoid prescription drugs.
Additional participating institutions include Duluth Clinic CCOP, Duluth, MN (Daniel A. Nikcevich, MD, PhD); CCOP Sioux Community Cancer Consortium, Sioux Falls, SD (Loren K. Tschetter, MD); Iowa Oncology Research Association CCOP, Des Moines, IA (Robert J. Behrens, MD); Mayo Clinic Arizona, Scottsdale AZ (Tom R. Fitch, MD); Missouri Valley Cancer Consortium CCOP, Omaha, NE (Gamini S. Soori, MD); Medical College of Georgia Minority-Based CCOP, Augusta, GA (Anand P. Jillella, MD); Columbus CCOP, Columbus, OH (J. Philip Kuebler, MD, PhD); Upstate Carolina CCOP, Spartanburg, SC (James D. Bearden, MD); Cedar Rapids Oncology Project CCOP, Cedar Rapids, IA (Martin Wiesenfeld, MD); Altru Cancer Center, Grand Forks, ND (Todor Dentchev, MD); Montana Cancer Consortium CCOP, Billings, MT (Benjamin T. Marchello, MD); Saint Vincent Hospital CCOP, Green Bay, WI (Anthony J. Jaslowski, MD); Colorado Cancer Research Program CCOP, Denver, CO (Eduardo R. Pajon, Jr, MD); Geisinger Medical Center CCOP, Danville, PA (Albert M. Bernath, Jr, MD); Rapid City Regional Hospital, Rapid City, SD (Richard C. Tenglin, MD); Siouxland Hematology Oncology Associates, Sioux City, IA (Donald B. Wender, MD, PhD); Toledo Community Hospital Oncology Program CCOP, Toledo, OH (Paul L. Schaefer, MD).
Correspondence to: Debra L. Barton, RN, PhD, AOCN, FAAN, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905; telephone: 507-255-3812; fax: 507-538-8300
