Gene Expression Signatures in Breast Cancer: A Surgical Oncologist’s Perspective
Gene expression can serve to supplement the assessment of recurrence risk now used as the basis for chemotherapy or estrogen ablation recommendations for patients with breast cancer.
CONCLUSION
Gene expression signatures provide information about the biologic behavior of each individual patient’s breast cancer. As new GES are introduced into clinical practice, surgeons must become fully informed about these advances in order to provide truly personalized cancer care plans to our patients.
Author disclosures
The author reports no actual or potential conflicts of interest with regard to this article.
Disclaimer
The opinions expressed herein are those of the author and do not necessarily reflect an endorsement by or opinion of Federal Practitioner, Frontline Medical Communications, the U.S. Air Force, the U.S. Government, or any of its agencies. This article may discuss unlabeled or investigational use of certain drugs. Please review complete prescribing information for specific drug combinations–including indications, contraindications, warnings, and adverse effects–before administering pharmacologic therapy to patients.
