Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Occupational Cleaning & Lung Function Decline

Am J Respir Crit Care Med; ePub 2018 Feb 16; Svanes, et al

Women cleaning at home or working as occupational cleaners had accelerated decline in lung function, a recent study found. The ECRHS study, which has investigated a multicenter population based cohort at 3 time points over 20 years, included 6,230 participants with at least 1 lung function measurement from 22 study centers. Researchers found:

  • Compared to women not engaged in cleaning, forced expiratory volume (FEV1) declined more rapidly in women responsible for cleaning at home (-22.1, p=0.01) and occupational cleaners (-22.4, p=0.03).
  • The same was found for decline in forced vital capacity (FVC).
  • Both cleaning sprays and other cleaning agents were associated with accelerated FEV1 decline (-22.0, p=0.04 and -22.9, p=0.0004, respectively).
  • Cleaning was not significantly associated with lung function decline in men or with chronic airway obstruction.

Citation:

Svanes Ø, Bertelsen RJ, Lygre SH, et al. Cleaning at home and at work in relation to lung function decline and airway obstruction. [Published online ahead of print February 16, 2018]. Am J Respir Crit Care Med. doi:10.1164/rccm.201706-1311OC.

This Week's Must Reads

CVD Events Prevented with New AHA BP Guideline, Circulation; ePub 2018 Nov 19; Bress, et al

USPSTF: Interventions to Prevent Child Maltreatment, JAMA; 2018 Nov 27; US Preventive Services Task Force

Team-Based Primary Care in Chronically Ill Patients, JAMA Intern Med; ePub 2018 Nov 26; Meyers, et al

Rotating Night Shift Work & Risk of T2D, BMJ; ePub 2018 Nov 21; Shan, Li, et al

PUFAs for Primary & Secondary CVD Prevention, Cochrane Library; ePub 2018 Nov 27; Abdelhamid, et al

Must Reads in Pulmonology

Occupational Cleaning & Lung Function Decline, Am J Respir Crit Care Med; ePub 2018 Feb 16; Svanes, et al

Should Patients with Syncope be Evaluated for PE?, JAMA Intern Med; ePub 2018 Jan 29; Costantino, et al

Are Shorter Regimens of TB Infection Tx Safe?, Pediatrics; ePub 2018 Jan 23; Cruz, et al

Assessing Mepolizumab for Eosinophilic COPD, N Engl J Med; ePub 2017 Oct 26; Pavord, et al

LAMA + LABA for Patients with Stable COPD, JAMA; 2017 Oct 3; Horita, Nagashima, et al