Cortical Thickening Observed in Patients With Frequent Migraines

Additional functional MRI comparing somatosensory cortex connectivity between migraine groups showed that certain other areas of the brain were also more active in the high-frequency group.

"Interestingly, all of these areas ... are known areas involved in pain processing," she noted. "So again, this confirms that this thicker cortical area in high-frequency migraineurs also has stronger communication with these other areas of the brain that are also involved in pain processing."

Dr. Maleki disclosed no relevant conflicts of interest. Data analysis was supported in part by a grant from Merck.