Nancy A. Melville

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Hemophilia: Novel Tx Also Cuts Bleeding in Kids

Author:: Nancy A. Melville

Publish date: July 22, 2024

For pediatric patients with hemophilia A, once-weekly factor VIII prophylaxis shows bleeding protection similar to that for adults.

News

What Should Be Prioritized in Managing Early Diabetes?

Author:: Nancy A. Melville

Publish date: July 3, 2024

ADA meeting debate on what to treat first in early diabetes included obesity, glucose, remission as priorities.

News

Hemophilia: Marstacimab Sustains Long-Term Bleeding Reduction

Author:: Nancy A. Melville

Publish date: June 26, 2024

In an interim analysis, this novel, weekly subcutaneous injection shows continued benefits in the prevention of bleeding in hemophilia A and B.

News

Pancreatic Gene Therapy: A ‘One-and-Done’ GLP-1 Treatment?

Author:: Nancy A. Melville

Publish date: June 26, 2024

A single-dose pancreatic gene therapy may compare with GLP-1 effect, a mouse model study finds.

News

DLBCL: Glofitamab Plus Chemo Boosts Survival

Author:: Nancy A. Melville

Publish date: June 20, 2024

The bispecific antibody glofitamab, combined with chemotherapy, significantly improves overall survival in second-line treatment of DLBCL.

News

APL: Should Chemo-Free Regimen Become New Standard?

Author:: Nancy A. Melville

Publish date: June 20, 2024

Fresh data indicates that the benefits of a chemo-free regimen also extend to the treatment of high-risk acute promyelocytic leukemia.

News

Myeloma: First-In-Class ADC Regimen Yields Key Benefits

Author:: Nancy A. Melville

Publish date: June 6, 2024

Patients with relapsed/refractory multiple myeloma show significant improvements in PFS when treated with an antibody-drug conjugate.

News

CML: Asciminib Bests Standard TKIs as Frontline Therapy

Author:: Nancy A. Melville

Publish date: June 3, 2024

For CML, this potent, highly selective TKI significantly improves molecular responses, reduces discontinuations versus standard TKIs.

News

Semaglutide Kidney Benefits Extend to Those Without Diabetes

Author:: Nancy A. Melville

Publish date: May 31, 2024

The kidney benefits observed in patients who are at high risk of kidney disease but do not yet have diabetes or chronic kidney disease is encouragi...

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Outside the Guidelines: Prostate Cancer Screening Overused in Older Men

Author:: Nancy A. Melville

Publish date: May 15, 2024

Experts address potential harms of screening for prostate cancer in patients with low life expectancy.

News

Tackling Lean Mass Loss When Weight Loss is Successful

Author:: Nancy A. Melville

Publish date: May 15, 2024

Clinicians should consider the impact of lean mass loss, not just overall weight loss, when patients lose weight with GLP-1s.

News

Kids and Anti-Obesity Medications: Real-World Challenges

Author:: Nancy A. Melville

Publish date: May 10, 2024

Prescribing anti-obesity medications comes with challenges ranging from accessing and affording the medications t...

News

What Underlies Sex Differences in CKD Cardiovascular Risk?

Author:: Nancy A. Melville

Publish date: May 6, 2024

It is important to recognize sex differences in sympathetic nervous activity when assessing cardiovascular risk in CKD.

News

Genetic Signatures May Predict CAR T Responders

Author:: Nancy A. Melville

Publish date: April 24, 2024

Research data suggest that key genetic clues of patients with LBCL could show which are more — or less — likely to respond to axi-cel CAR T.

News

Tiny Doses of Metabolically Armed CAR T Show Benefits

Author:: Nancy A. Melville

Publish date: April 23, 2024

The IL-10-expressing Meta10-19 CAR T-cell therapy improved outcomes in B-ALL and DLBCL at doses 5% and lower of standard CAR T products.