Nancy A. Melville

News

Four Key Genes Linked to Worse Gastric Cancer Outcomes

Author:: Nancy A. Melville

Publish date: April 29, 2025

While treatment strategies in gastric cancer have improved in recent years, resistance to multiple drugs continues, and the 5-year overall survival...

News

Inadequate Grading of Intraductal Carcinoma of the Prostate

Author:: Nancy A. Melville

Publish date: March 28, 2025

Article

Thyroid Cancer Detections Due to More Screenings With GLP-1s

Author:: Nancy A. Melville

Publish date: January 28, 2025

Higher cancers detected in first year likely from higher screening.

Article

GLP-1s Have Real-World Benefits and Risks In Large Scale VA Study

Author:: Nancy A. Melville

Publish date: January 27, 2025

Researchers found reduced risk for alcohol and opioid use, suicidal ideation, and cardiac arrest among others.

News

FL: Tafasitamab Plus Combo Boosts Outcomes

Author:: Nancy A. Melville

Publish date: December 18, 2024

The combination of anti-CD19 and CD20 monoclonal antibodies could represent a “new standard of care” in treating follicular...

News

Upfront Therapy for ITP in Children: New Drug a Game-Changer?

Author:: Nancy A. Melville

Publish date: December 17, 2024

Eltrombopag shows improved platelet counts and quality of life outcomes in treating pediatric immune thrombocytopenia.

News

Multiple Myeloma: Dexamethasone-Sparing Approach Benefits Frail Older Adults

Author:: Nancy A. Melville

Publish date: December 13, 2024

Study of elderly, frail patients with myeloma shows reduced disease progression and death with a regimen that decreased dexamethasone exposure.

News

High-Fiber Diet Linked to Improved Stem Cell Transplant, GvHD Outcomes

Author:: Nancy A. Melville

Publish date: December 9, 2024

While low-fiber diets are typically recommended during transplant, patients with higher fiber diets show improved survival and reduced risk of graf...

News

How to Stop Bone Loss After Denosumab? No Easy Answers

Author:: Nancy A. Melville

Publish date: November 21, 2024

One year after replacement with zoledronate, reversals of denosumab’s gains in lumbar spine BMD are seen — with longer denosumab use linked to grea...

News

Update Coming for Thyroid Disease in Pregnancy Guidelines

Author:: Nancy A. Melville

Publish date: November 11, 2024

Age over 30 years, having at least two prior pregnancies, and morbid obesity (body mass index [BMI] at least 40 kg/m²), will no longer b...

News

Myeloma: Isa-KRd Induction Shows High MRD Responses

Author:: Nancy A. Melville

Publish date: October 9, 2024

Interim analysis of first MIDAS trial findings shows “highest rate of response and MRD negativity to date.”

News

Daratumumab Quadruplet Supported Transplant-Ineligible MM

Author:: Nancy A. Melville

Publish date: October 3, 2024

A phase-3 study showed that adding daratumumab to VRd yields a primary endpoint of MRD negativity in patients newly diagnosed with myeloma.

News

Myeloma: Daratumumab Plus Lenalidomide Improves MRD Outcomes

Author:: Nancy A. Melville

Publish date: September 30, 2024

New research shows that adding daratumumab to maintenance therapy improves MRD and PFS outcomes in multiple myeloma.

News

SGLT2 Inhibitor Reduces Risk for Neurodegenerative Diseases in T2D

Author:: Nancy A. Melville

Publish date: September 16, 2024

Those receiving SGLT2i treatment had a 21% reduced risk for all-cause dementia and a 22% reduced risk for all-cause dementia and Parkinson’s diseas...

News

After Rapid Weight Loss, Monitor Antiobesity Drug Dosing

Author:: Nancy A. Melville

Publish date: August 15, 2024

Toxicities from excessive doses can have a range of detrimental effects; examine dosing following rapid weight loss.