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NGS can predict AML relapse after HSCT

Author:
HT Staff
Publish date: September 21, 2018

Next-generation sequencing (NGS) can be used to predict relapse in acute myeloid leukemia (AML) patients undergoing hematopoietic stem cell...

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Trial sponsors fail to comply with EU rules

Author:
HT Staff
Publish date: September 21, 2018

Sponsors of clinical trials often do not comply with European Union (EU) rules on reporting results, according to a new study. Researchers looked...

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Stress linked to disease markers in CLL

Author:
HT Staff
Publish date: September 20, 2018

New research has linked stress levels to markers of progressive disease in patients with chronic lymphocytic leukemia (CLL). Researchers found...

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News

NICE rejects DLBCL indication for CAR T-cell therapy

Author:
HT Staff
Publish date: September 20, 2018

The National Institute for Health and Care Excellence (NICE) has issued a draft guidance saying it cannot recommend tisagenlecleucel (Kymriah) as...

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News

OBI-3424 receives orphan designation for ALL

Author:
HT Staff
Publish date: September 20, 2018

The U.S.

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ASCO addresses financial barriers to cancer clinical trials

Author:
HT Staff
Publish date: September 18, 2018

The American Society of Clinical Oncology (ASCO) has issued a policy statement addressing financial barriers to patient participation in cancer...

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News

Doc reports ‘very encouraging’ results in penta-refractory MM

Author:
HT Staff
Publish date: September 17, 2018

HOUSTON—Treatment with selinexor and low-dose dexamethasone can provide a “meaningful clinical benefit” in patients with penta-refractory multiple...

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CAR T-cell therapy elicits responses in MM

Author:
HT Staff
Publish date: September 15, 2018

BOSTON—Early results from a phase 1 trial suggest the chimeric antigen receptor (CAR) T-cell therapy P-BCMA-101 can produce responses in patients...

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Kids with BCP-ALL exhibit immunological disparities at birth

Author:
HT Staff
Publish date: September 14, 2018

Patients who develop B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in childhood may have dysregulated immune function at birth,...

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News

FDA approves drug for hairy cell leukemia

Author:
HT Staff
Publish date: September 14, 2018

The U.S.

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News

EC approves product for von Willebrand disease

Author:
HT Staff
Publish date: September 14, 2018

The European Commission (EC) has granted marketing authorization for vonicog alfa (Veyvondi), a recombinant von Willebrand factor (rVWF) product...

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Insights could change treatment, classification of MPAL

Author:
HT Staff
Publish date: September 13, 2018

An extensive analysis of mixed phenotype acute leukemia (MPAL) has led to new insights that may have implications for disease classification and...

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News

MRD data added to venetoclax label

Author:
HT Staff
Publish date: September 12, 2018

The U.S.

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Cell population appears to drive relapse in AML

Author:
HT Staff
Publish date: September 11, 2018

Researchers believe they have identified cells that are responsible for relapse of acute myeloid leukemia (AML). These “leukemic-regenerating...

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News

HIF1A could be therapeutic target for MDS

Author:
HT Staff
Publish date: September 11, 2018

The transcription factor HIF1A could be a therapeutic target for “a broad spectrum” of patients with myelodysplastic syndromes (MDS), according to...

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