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Gene expression pattern in Crohn’s linked to treatment resistance
A pattern of cellular gene expression in some patients with Crohn’s disease is associated with resistance to anti-TNF therapy.
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Weight loss surgery linked to lower CV event risk in diabetes
Metabolic surgery was associated with a significantly lower cumulative incidence of myocardial infarction, ischemic stroke, and mortality than...
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COMPLETE revascularization reduces death and recurrent MI risk
Complete revascularization of nonculprit lesions after STEMI could significantly reduce the risk of death or recurrent myocardial infarction.
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Hemophilia carriers face elevated risk of joint comorbidities
Individuals who carry hemophilia genes and have reduced clotting factor activity also have a higher risk of joint-related comorbidities.
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Endometriosis is linked to adverse pregnancy outcomes
Women with endometriosis have a greater risk of adverse pregnancy outcomes including ectopic pregnancy, preterm birth, and gestational diabetes....
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Fifty-one percent of U.S. adolescents fully vaccinated against HPV
The increase this year was attributable only to an increase in HPV vaccination among male teens.
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Hidradenitis suppurativa linked to higher NAFLD risk
Patients with hidradenitis suppurativa show a significantly higher rate of nonalcoholic fatty liver disease than people without hidradenitis...
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Cancer survivors face more age-related deficits
Cancer survivors are more likely to experience age-related health deficits and increased mortality, compared with people without a history of...
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Cardiovascular cost of smoking may last up to 25 years
While quitting smoking significantly reduces the risk of cardiovascular disease within five years, the elevated risk can persist for up to 25...
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Self-reported falls can predict osteoporotic fracture risk
Over an almost 3-year period, about 3.5% of the population experience a major osteoporotic fracture.
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Analysis finds no mortality reductions with osteoporosis drugs
A meta-analysis has found no evidence that osteoporosis drugs are associated with a reduction in mortality.
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Bisphosphonates improve BMD in pediatric rheumatic disease
Children and adolescents whose chronic rheumatic disease is treated with steroids could benefit from bisphosphonate therapy to improve bone...
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Timing of adjuvant treatment impacts pancreatic cancer survival
Patients who received adjuvant therapy 28-59 days after surgery had the best survival rates in a cohort study of 7,548 patients with stage I-II...
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Algorithm boosts MACE prediction in patients with chest pain
High-sensitivity cardiac troponin measurements combined with ECG and clinical assessment can help rule out MACE and unstable angina.
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Aspirin interacts with epigenetics to influence breast cancer mortality
Prediagnosis aspirin use appears to influence breast cancer mortality in women with certain epigenetic changes to particular breast cancer–related...