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IPD in children may be a signal of immunodeficiency
Children with invasive pneumococcal disease may have a higher likelihood of underlying primary immunodeficiencies.
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Few antidepressant adverse effects backed by convincing evidence
"The results showed that the association ... was not supported by robust evidence and that the underlying disease likely inflated the findings...
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Higher teen pregnancy risk in girls with ADHD
Women and girls with ADHD may be at significantly greater risk of pregnancy before age 20.
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Zostavax proves safe, effective in patients with nonactive SLE
The live-attenuated herpes zoster vaccine appears safe and effective in individuals with nonactive systemic lupus erythematosus.
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Secondary prevention of osteoporotic fractures lacking
Osteoporotic fractures contribute significant health costs to the United States, yet secondary prevention efforts are lagging.
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Obesity, moderate drinking linked to psoriatic arthritis
Reduction in body mass index over time also was associated with lower risk of developing psoriatic arthritis.
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Meta-analysis finds platelet-rich plasma may improve hair growth
Five studies reported statistically significant increases in hair density in favor of PRP over placebo.
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Postdural puncture headache linked to increased risk of subdural hematoma
The subdural hematoma rate increased slightly, but significantly, to 147 per 100,000 deliveries.
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Prior antibiotic use lowers checkpoint inhibitor response and survival
Patients who take antibiotics in the 30 days prior to starting checkpoint inhibitor therapy for cancer have significantly lower overall survival...
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No decrease in preterm birth with n-3 fatty acid supplements
Women taking n-3 fatty acid supplements during pregnancy were more likely to have infants that were very large for their gestational age than were...
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Chronic hypertension in pregnancy increased 13-fold since 1970
There was a significant racial disparity in the rates of chronic hypertension.
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Pediatric HSCT recipients still risking sunburn
Pediatric hematopoietic stem cell transplant recipients are practicing more sun-protection behaviors, but they still tan and sunburn as much as...
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Migraines linked to higher risk of dementia
People with a history of migraines may be at greater risk of developing Alzheimer’s disease and dementia.
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Modifiable risk factors account for many gout cases
A substantial proportion of gout cases are attributable to four modifiable lifestyle risk factors, including BMI and alcohol intake.
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SAGE-217 shows reduction in depression with no safety concerns
A new oral antidepressant targeting GABAA receptors shows significant improvements in depression scores with no major safety signals....