From the Journals

Unusual skin reactions to aluminum patch test seen in some children



Two young girls who were patch tested for aluminum contact allergy because of persistent pruritic postvaccinal nodules had atypical results. Instead of the usual eczematous reaction confined to the test area, they exhibited erythema and papules distant from the test area.

In one girl, the reaction consisted of erythematous itchy papules across much of her back on day 2, and by day 4, there were even papules on her chest. In the other girl, erythema, infiltration, and occasional papules covered the whole patch area, and erythematous papules also were seen at some distance from the test area, Nadia Raison-Peyron, MD, of Saint-Eloi Hospital, Montpellier, France, and her colleagues, reported in Pediatric Dermatology.

Vaccine syringe luiscar/Thinkstock
The patch tests had been given because of itchy reactions to aluminum-adsorbed vaccines; children with such reactions often have positive patch test results for aluminum contact allergies. The girls had received the same vaccines that gave rise to those reactions previously without issue.

Biopsies were not performed because of the girls’ young age.

SOURCE: Raison-Peyron N et al. Pediatr Dermatol. 2018. doi: 10.1111/pde.13481.

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