Left subconjunctival hemorrhage • renal dysfunction • international normalized ratio of 4.5 • Dx?
The Journal of Family Practice. 2015 October;64(10):E3-E4
October 1, 2015|The Journal of Family Practice
Author and Disclosure Information
THE TAKEAWAY
Dabigatran may cause elevated INR levels in patients with renal dysfunction and/or those taking other medications that could interact with dabigatran. Concurrent use of any P-gp inhibitor (such as tacrolimus) and dabigatran is contraindicated in patients with severe renal dysfunction. Despite the lack of required routine laboratory monitoring, renal function and drug interactions associated with dabigatran therapy should be monitored closely.
