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Association between serum magnesium concentration and postmenopausal osteoporosis

Key clinical point: Postmenopausal women with osteoporosis have a lower concentration of serum magnesium (Mg). However, the association between serum Mg concentration and osteopenia is not significant.

Major finding: Serum Mg concentration was lower in postmenopausal women with osteoporosis vs. healthy controls (standardized mean difference [SMD], −0.56; 95% confidence interval [CI], −1.02 to −0.09). However, the concentration of serum Mg did not differ between those with osteopenia and healthy controls (SMD, −0.30; 95% CI, −0.69 to 0.09).

Study details: A meta-analysis of 11 studies including 2,776 postmenopausal women.

Disclosures: The study was financially supported through grants from the Natural Science Foundation of Shandong Province, the Medical and Health Science and Technology Development Project of Shandong Province, the Clinical Medical Science and Technology Innovation Program of the Jinan Science and Technology Bureau, and the Traditional Chinese Medicine Technology Development Plan of Shandong Province. The authors declared no conflicts of interest.


Chang J et al. Front Med. 2020 Aug 4. doi: 10.3389/fmed.2020.00381.