Tolvaptan Safely Improves Heart Failure Symptoms

“Clinicians should be encouraged to continue to use diuretics judiciously as needed. … Adjunctive short-term arginine vasopressin antagonism may be considered for the patient with established low [ejection fraction],” Dr. Yancy wrote.

Betsy Bates contributed to this report from New Orleans.

Dr. Marvin A. Konstam, of Tufts-New England Medical Center, said that he was “disappointed” that the agent failed to reduce mortality or heart failure-related morbidity either during hospitalization or at 1-year follow-up. Catherine Hackett/Elsevier Global Medical News