Geriatrics
Conference Coverage
Noncardiac surgery has 7% covert stroke rate in elderly
HONOLULU – Covert strokes were linked with a doubled rate of cognitive decline in older patients after noncardiac surgery.
News from the FDA/CDC
FDA issues warnings to companies selling illegal Alzheimer’s treatments
The FDA targeted more than 58 products.
From the Journals
Exercise type matters for fall prevention among elderly
Balance and functional exercises are best at preventing falls.
From the Journals
Novel plasma biomarkers may predict preclinical Alzheimer’s disease
The approach will need to be validated and translated “to a simpler automated platform suitable for wider utility.”
From the Journals
Statins cut vascular events in elderly patients
Analysis challenges current practice of discontinuation after age 75 years.
Feature
Phase 3 studies of antiamyloid Alzheimer’s drug crenezumab stopped
The molecule will continue to be tested in a study of familial Alzheimer’s in Colombia.
From the Journals
SPRINT MIND published: Extension trial to add 2 years’ follow-up
From the Journals
Long-term opioid use substantial in elderly adults prior to total joint replacement
From the Journals
Potential antidepressant overprescribing found in 24% of elderly cohort
Overprescribing of SSRIs accounted for 74% of all antidepressant overprescriptions, followed by mirtazapine (19%).
Conference Coverage
Ezetimibe found effective for primary prevention in elderly
CHICAGO – Japanese EWTOPIA 75 study provides first RCT evidence of benefit for LDL-lowering in seniors.
News
Frailty may affect the expression of dementia
People with higher degrees of frailty may be more likely to have more Alzheimer’s disease pathology and clinical dementia.