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Breast Cancer Drug Exemestane Linked to BMD Loss

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Adverse Bone Effects ‘Substantially Underestimated’ Until Now

FROM THE LANCET ONCOLOGY

This substudy was supported by the Canadian Breast Cancer Research Alliance, a joint initiative between the Canadian Institutes of Health Research and the Canadian Cancer Society. The main MAP.3 study also was supported by Pfizer. Jamieson Laboratories provided calcium and vitamin D supplements and Pfizer Pharmaceuticals provided exemestane and placebo. Dr. Cheung is supported in part by a Canadian Institutes of Health Research/Institute of Gender and Health Senior Investigator Award, and the Lillian Love Chair in Women’s Health at the University of Toronto/University Health Network. One of Dr. Cheung’s associates reported ties to Pfizer and Avon Foundation. None of the other researchers reported conflicts of interest.