Antidepressant use linked to increased weight gain

“From a clinical perspective, these observations reinforce the need for active body weight management to accompany widespread antidepressant treatment, although this might often be met with limited success,” the authors wrote. “The potential for weight gain may also be a consideration in the selection of individual antidepressant drugs.”

The research was funded by the National Health Service Foundation Trust and by King’s College London. Aside from one author’s employment with the U.K. Clinical Practice Research Datalink data source, the authors had no disclosures.

SOURCE: Gafoor R et al. BMJ. 2018;361:k1951. doi: 10.1136/bmj.k1951.