From the Journals

Office-based screen predicts dementia in Parkinson’s disease


 

FROM JAMA NEUROLOGY

A simple, office-based screening tool was at least as effective as biomarker-based assessments in predicting which patients with Parkinson’s disease are likely to develop dementia in an international study.

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After a mean follow-up of 4.4 years, 11.5% of the study cohort developed dementia. Those who were stratified by the scale as having a low risk of dementia had an annual risk of 0.6%. Those in the intermediate-risk group had a 5.8% annual risk of developing dementia, and those in the high-risk group had a 14.9% annual risk.

Compared with patients in the low-risk group, those in the high-risk group had a 20-fold higher risk of dementia, and those in the intermediate risk group had a 10-fold higher risk (P less than 0.001).

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