Bleeding Disorders
Conference Coverage
LentiGlobin reduces transfusion dependence in young thalassemia patients
NEW ORLEANS – Children and young adults with non-beta0/beta0 thalassemia achieved transfusion independence in two trials.
Conference Coverage
TTP death linked to elevated troponin and neurological signs
GLASGOW – The registry-based study showed that more than 70% of patients who presented with thrombotic thrombocytopenic purpura had neurological...
From the Journals
Extended half-life clotting factors cut infusions, hike prices
The use of extended half-life clotting factors was able to significantly reduce the number of infusions but the cost went up significantly.
From the Journals
HAVEN 4: Monthly emicizumab shows value
Emicizumab was effective as a monthly treatment for patients with hemophilia A, both with and without inhibitors, according to an ongoing phase 3...
From the Journals
New consensus recommendations on vaccination in hemophilia
Vaccination in patients with hemophilia should be provided on the same institutional schedule but planning should take into account disease-...
From the Journals
Study explores intracranial hemorrhage management in type 2 VWD
The case report on spontaneous intracranial hemorrhage in a patient with type 2B von Willibrand disease illustrates the lack of standard...
From the Journals
Genetic analysis detects novel gene mutations in hemophilia A
Researchers identified two novel mutations that resulted in a severe phenotype of hemophilia A.
From the Journals
Platelet-rich plasma shows promise in hemophilic arthropathy of the knee
A single injection of platelet-rich plasma performed better on measures of function and pain than did weekly injections of hyaluronic acid.
From the Journals
Women with FXI deficiency face hemorrhage risk with gyn surgery
The 20-year retrospective analysis found the highest proportion of bleeding after gynecologic surgery.
From the Journals
Study finds higher than expected rates of hemophilia in Indiana
The rise could be caused by increased use of prophylaxis and improvements in HIV care that are cutting mortality in the hemophilia population.
Feature
SB-525 gene therapy looks viable for hemophilia A
Two of eight patients treated with the investigational gene therapy SB-525 have achieved normal factor VIII levels, according to interim study...