Similar long-term outcomes after colorectal surgery in ulcerative colitis-associated vs. sporadic CRC

Key clinical point: Long-term oncological outcomes after colorectal surgery were not significantly different among patients with ulcerative colitis-associated colorectal cancer (CRC) and sporadic CRC.

Major finding: Disease-free survival (hazard ratio [HR], 1.06; 95% confidence interval [CI], 0.85-1.32), recurrence-free survival (HR, 1.14; 95% CI, 0.86-1.53), and all-cause mortality (HR, 1.15; 95% CI, 0.89-1.48) were similar between the group of patients with ulcerative colitis-associated and sporadic CRC.

Study details: This observational cohort study included 1,332 patients who underwent surgery with curative intent for CRC including 222 patients with a preoperative diagnosis of ulcerative colitis who were matched with 1,110 patients with sporadic CRC.

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Disclosures: The study did not receive any funding. The authors declared no commercial interest in the subject of the study.

Source: Lin VA et al. Ann Surg Oncol. 2021 Sep 5. doi: 10.1245/s10434-021-10759-8.