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MDS: Low lymphocyte-to-monocyte ratio predicts better outcomes

Clinical Edge Journal Scan: MDS May 2021 (1 of 11)

Key clinical point: Low lymphocyte-to-monocyte ratio (LMR) in patients with myelodysplastic syndrome (MDS) is associated with a favorable prognosis.

Major finding: LMR lesser than vs. greater than 5 was associated with a lower risk for leukemic transformation (median time not reached; P = .003) and better leukemia-free survival (median, 48 months vs. 21 months; P = .03).

Study details: Findings are from a retrospective study of 201 patients with a new diagnosis of MDS.

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Disclosures: No source of funding was declared. The authors declared no potential conflicts of interest.

Source: Pénichoux J et al. Leuk Lymphoma. 2021 Apr 2. doi: 10.1080/10428194.2021.1907381