Anemia
News
First advance in MDS for decade: Luspatercept for anemia
Luspatercept has been approved by the FDA to treat anemia in patients with myelodysplastic syndromes.
From the Journals
Low plasma sodium predicts complications in SCD acute pain episodes
Hyponatremia was associated with acute chest syndrome (OR 1.95, P = .008) and red blood cell...
Feature
New sickle cell drugs give hope, but access remains a barrier
"SCD reduces lifespan by 30 years, and that's very hard to quantify," says Dr. Ifeyinwa Osunkwo.
From the Journals
Sickle cell patients with vitamin D deficiency prone to more ED visits, longer stays
Screening for vitamin D deficiency may show benefits, authors suggest.
From the Journals
Chimerism and the use of fludarabine associated with secondary graft failure in aplastic anemia
From the Journals
Genetic testing helps avoid false hemoglobinopathy diagnoses in newborns
“We now perform simultaneous protein-based and genetic testing as our standard clinical practice.”
From the Journals
Flow-mediated dilation of brachial artery predicts renal dysfunction in sickle cell disease
Conference Coverage
Deferiprone noninferior to deferoxamine for iron overload in SCD, rare anemias
An oral iron chelator granted accelerated approval for thalassemia is noninferior to deferoxamine for iron overload in patients with sickle cell...
Conference Coverage
Sevuparin failed for acute VOC in sickle cell, but may have preventive potential
The novel nonanticoagulant heparinoid drug sevuparin may have value in the setting of prodromal vaso-occlusive crisis in patients with SCD.
Commentary
The evolving landscape of complement inhibition therapy
The surge of new complement inhibitors could revolutionize our strategy for treatment of autoimmune-mediated diseases.
Conference Coverage
BCL11A-directed gene therapy advances in sickle cell disease
ORLANDO – A phase 2/3 study is planned to assess the gene therapy in a larger group of patients with sickle cell disease.