Hepatocellular Carcinoma: To Biopsy or Not?

Hepatocellular carcinoma (HCC) accounts for 90% of all primary liver cancers and is the third leading cause of cancer-related mortality. Although HCC is often deadly, it is potentially curable if diagnosed at an early stage. Generally, needle biopsy of a suspicious liver lesion is not recommended because it raises the risk of needle track seeding.