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Angiography timing shown not a risk for AKI in most cardiac surgery

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FROM THE INTERNATIONAL JOURNAL OF CARDIOLOGY

Unadjusted analysis of the total cohort showed AKI was significantly associated with contrast exposure within 1 day of surgery. However, in multivariable analysis, the time interval between catheterization and surgery as both a categorical and continuous variable was not an independent predictor of postoperative AKI for the total cohort. In subgroup analysis, only the combined valve and CABG group of patients showed an independent association of contrast exposure within 1 day before surgery and AKI in both the prematched (odds ratio, 2.69; P = .004) and the postmatched (OR, 3.68; P = .014) groups.

"Avoiding surgery within 1 day after contrast exposure should be recommended for patients undergoing valve surgery with concomitant CABG only. For other types of cardiac operations, delaying cardiac surgery after contrast exposure seems not to be justified," the researchers concluded.

Study limitations cited include its retrospective and single-institution nature and the statistical effect of different numbers of observations among the surgery groups. Patients affected with AKI also had higher rates of other postoperative complications, and AKI in some cases may have been the result of these rather than an independent event.

he study was supported by the Fondazione Cesare Bartorelli. The authors reported having no financial disclosures.

mlesney@frontlinemedcom.com