Nodular Extramammary Paget Disease With Fibroepitheliomatous Hyperplasia
Cutis. 2014 December;94(6):276-278
December 9, 2014|Cutis
Author and Disclosure Information
Extramammary Paget disease (EMPD) is a rare skin condition usually found in the anogenital region. Histologically, EMPD may be associated with varying degrees of epidermal hyperplasia classified as squamous, papillomatous, or fibroepitheliomatous. We report a case of EMPD in a 90-year-old man who presented with well-demarcated plaques and a nodule in the pubic area with fibroepitheliomatous hyperplasia.
Practice Points
- Extramammary Paget disease (EMPD) should be considered in the clinical differential diagnosis of verrucous nodules in the pubic area.
- Histopathologically, EMPD in the anogenital area could show fibroepitheliomatous hyperplasia with lacy strands of squamous epithelium.
Conclusion
Our case showed the unique finding of a verrucous nodular EMPD lesion in which peculiar histological features presented as extensions of the tumor cells forming lacy strands of squamous epithelium from the epidermis to the mid dermis as well as many glandular structures.
