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Regional Lymphomatoid Papulosis of the Breast Restricted to an Area of Prior Radiotherapy

Cutis. 2016 May;97(5):E15-E19
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We report the case of a 59-year-old woman with type A regional lymphomatoid papulosis (LyP) that was localized to the left breast, a cutaneous area that had received radiotherapy for treatment of a carcinoma of the breast 5 years prior. This report is a rare example of regional LyP with all lesions located in an area of prior radiotherapy.

Practice Points

  • Cutaneous lesions of lymphomatoid papulosis (LyP) sometimes are confined to only one area of the skin, which is known as regional LyP.
  • Patients with regional LyP have the same prognosis as those with widespread LyP, and no specific association has been reported with this clinical variant.
  • Lesions of regional LyP respond to the same treatments as widespread LyP.

Conclusion

In summary, we report an example of regional LyP limited to the left breast of a woman with a history of partial mastectomy and adjuvant radiotherapy for treatment of invasive ductal breast carcinoma. It is a rare case of regional LyP exclusively involving an irradiated area of the skin.