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Genetic Pathways, Part 2

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As part of our commitment to resident education, Cutis is excited to offer this monthly section with board-relevant, easy-to-review material.

This fact sheet details some of the important tumor suppressor pathways in dermatology and the clinical manifestations seen with these genetic derangements.

2. Bilateral acoustic neuromas are associated with what gene mutation?

a. NF1 (neurofibromin 1)

b. NF2 (neurofibromin 2)

,

c. PTCH1 (patched 1)

d. TSC1 (tuberous sclerosis 1)

e. TSC2 (tuberous sclerosis 2)