The correct interpretation includes normal sinus rhythm, possible left atrial enlargement (LAE), and left ventricular hypertrophy (LVH).
Normal sinus rhythm is defined as a P for every QRS and a QRS for every P, with a normal PR interval and a rate > 60 and < 100 beats/min.
Criteria for LAE include a P wave > 120 ms in lead II and/or a biphasic P wave in lead V1 with a downward deflection > 40 ms in length with a > 1-mm negative deflection. This ECG does not meet criteria for LAE; however, it is suspicious, particularly in the context of mitral regurgitation and LVH.
LVH is diagnosed using either the Sokolow-Lyon criteria (the sum of the S wave in V1 and the R wave in V5 or V6 ≥ 35 mm) or the Cornell voltage criteria (the S in V3 plus the R in aVL > 20 mm for women [> 28 mm for men]).
LVH is usually not a target of therapy. Management is typically directed at treating the underlying pathology. For this patient, it is important to manage her hypertension and provide follow-up—including periodic echocardiography of her left atrium, mitral valve, and left ventricle—to determine response to hypertensive therapy.