Michele G. Sullivan, Tara Haelle, Heidi Splete, Bianca Nogrady
Topics include: Later menopause lowers risk for later depression • Preschool ASD prevalence estimates lower than grade school estimates • Long-term PPI use linked to increased risk for dementia • Elevated cardiovascular risks linked to hidradenitis suppurativa
Here are 4 articles in the April issue of Clinician Reviews (individual articles are valid for one year from date of publication—expiration dates below):
1. Later Menopause Lowers Risk for Later Depression To take the posttest, go to: http://bit.ly/1U7I7f3 Expires January 6, 2017
VITALS Key clinical point:Later menopause, with its longer estrogen exposure, appears tied to a lower risk of postmenopausal depression. Major finding:The risk of depression decreased by 2% for each 2 premenopausal years after age 40. Data source:The meta-analysis comprised 14 studies with more than 67,700 women. Disclosures: Neither Dr. Georgakis nor any of the coauthors declared any financial conflicts.
2. Preschool ASD Prevalence Estimates Lower Than Grade School Estimates To take the posttest, go to: http://bit.ly/24Mec0X Expires January 5, 2017
VITALS Key clinical point: The prevalence of autism spectrum disorders among 4-year-olds is about 30% lower than among 8-year-olds. Major finding: Prevalence of ASD among 4-year-olds was 13/1,000 children across five U.S. states. Data source: A comparison of health and medical records for nationally representative cohorts involving 58,467 4-year-olds and 56,727 8-year-olds in five U.S. states in 2010. Disclosures: The Centers for Disease Control and Prevention funded the research. Dr. Christensen and her associates reported no disclosures.
3. Long-term PPI Use Linked to Increased Risk for Dementia To take the posttest, go to: http://bit.ly/1nrCdsb Expires February 24, 2017
VITALS Key clinical point:Proton pump inhibitors may add to the risk of dementia in older adults. Major finding: The risk of incident dementia was 44% higher in adults who used PPIs long term, compared with those who did not. Data source: The prospective cohort study included 73,679 adults aged 75 years and older. Disclosures: The researchers had no financial conflicts to disclose.
4. Elevated Cardiovascular Risks Linked to Hidradenitis Suppurativa To take the posttest, go to: http://bit.ly/1nrEFz3 Expires February 17, 2017
VITALS Key clinical point: Hidradenitis suppurativa is associated with a significantly increased risk of adverse cardiovascular events and all-cause mortality. Major finding: Individuals with hidradenitis suppurativa had a 57% greater risk of myocardial infarction and 33% greater risk of ischemic stroke, compared with the general population. Data source: A population-based cohort study in 5,964 patients with hidradenitis suppurativa. Disclosures: No conflicts of interest were declared.