More support for thrombectomy in large-core strokes: TESLA, MAGNA
“Noncontrast CT scans are available at all stroke centers so this study is more practical, highly generalizable, and more applicable globally.”
Preventive antipyretics, antibiotics not needed in stroke
“Remarkably, neither ceftriaxone nor metoclopramide had any effect on the risk of developing pneumonia. It was all quite disappointing.”
Intensive BP reduction after stroke recanalization harmful
The results suggest, “despite recanalization, some areas in the ischemic brain may have already been damaged,” or that surrounding areas continue...
Tenecteplase late after stroke misses endpoint: TIMELESS
“The most encouraging observation was that we did not show any safety issues with giving TNK to this population at such a late time.”
Cardiopathy no basis for choosing anticoagulation in ESUS
“It could be that this concept of thrombogenic atrial cardiopathy really isn’t present unless there is also atrial fibrillation.”
No added benefit from revascularization in low-risk CAS
“We are more aware of how we should treat” these patients, and “we’re probably a bit more aggressive,” which will have shifted the outcomes in the...
Care bundle improves outcome in ICH: INTERACT3
“This is a groundbreaking result. It is the first-ever published trial in ICH patients to show a clear benefit on functional outcomes and on...
Earlier anticoagulation safe in stroke with AFib: ELAN
“This trial will change clinical practice in that we can feel much more reassured that starting DOAC treatment early in these patients will not...
From the Journals
AHA urges action against racial inequities in stroke care
Insufficient research attention has been paid to reducing inequities in rehabilitation, recovery, and social reintegration, the writing group says...
From the Journals
A call to revamp revascularization trial endpoints
Coronary revascularization trials should focus more on quality of life than traditional composite outcomes, two trial investigators say.
Stroke scale cutoff might not be ideal guide for ordering CTA and detecting large vessel occlusions
If the goal is not to miss any LVOs, there is no NIHSS score below which these do not occur.