News
Antihistamines synergistically induce CLL cell death with TK inhibitors
- Author:
- Mark S. Lesney, PhD
Over-the-counter antihistamines induced synergistic cytotoxicity with TK inhibitors.
News
Polygenic risk score may predict VTE in adolescents, but not adults, with ALL
- Author:
- Mark S. Lesney, PhD
A genetic risk score predicted which acute lymphoblastic leukemia–affected adolescents were more at risk of a...
News
Elotuzumab-based therapy may benefit post-transplant response in multiple myeloma
- Author:
- Mark S. Lesney, PhD
Elotuzumab-based maintenance may deepen response post transplant in MM and can be safely administered in older...
News
BALL score predicts benefit from ibrutinib therapy in relapsed/refractory CLL patients
- Author:
- Mark S. Lesney, PhD
The BALL score outperformed three other scores in providing the best prediction of an overall survival benefit...
Opinion

Chronicles of cancer: A history of mammography, part 1
- Author:
- Mark S. Lesney, PhD
Tied to the rise of technology and the women's rights movement, the story of mammography is a touchstone for the history of cancer screening and...
News
Posaconazole prophylaxis was effective in children with ALL undergoing chemotherapy
- Author:
- Mark S. Lesney, PhD
Targeted posaconazole prophylaxis was effective in preventing invasive fungal infection in children with ALL undergoing induction chemotherapy.
News
MM patients with concurrent AL show poor survival when coupled to cardiac dysfunction
- Author:
- Mark S. Lesney, PhD
Cardiac dysfunction is a major determinant of poor survival in multiple myeloma patients with concurrent light chain amyloidosis.
News
HSCT or systemic treatment should be offered to HIV+ patients with lymphoma
- Author:
- Mark S. Lesney, PhD
Patients with lymphoma and HIV infection benefit from systemic or stem cell therapy, but with worse outcomes...
News
Heavy menstrual bleeding difficult to control in young patients with inherited platelet disorders
- Author:
- Mark S. Lesney, PhD
Consensus and a broadly effective treatment for heavy menstrual bleeding was not found among the patients with inherited platelet function...
News
Transitioning regimen may prolong proteasome inhibitor–based therapy for MM
- Author:
- Mark S. Lesney, PhD
Transitioning from parenteral bortezomib-based induction to all-oral ixazomib-lenalidomide-dexamethasone increased PI-based treatment adherence/...
News
FDA approves selinexor for relapsed/refractory DLBCL
- Author:
- Mark S. Lesney, PhD
Selinexor is approved for adults with relapsed/refractory DLBCL, including DLBCL arising from follicular...
News
Oxidatative stress–related genetic variant tied to stroke risk in sickle cell patients
- Author:
- Mark S. Lesney, PhD
SOD2 Val16Ala polymorphism may represent a simple and inexpensive alternative for identifying sickle cell patients at risk of stroke.
News
First-in-kind anti-CD47 antibody shows promise for MDS and AML treatment
- Author:
- Mark S. Lesney, PhD
Magrolimab/azactydine (AZA) improved outcomes in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS...
News

Subcutaneous hep A vaccination as effective as intramuscular for bleeding disorder patients
- Author:
- Mark S. Lesney, PhD
Subcutaneous hepatitis A vaccination is as effective and may be safer for patients with bleeding disorders....
News

Added rituximab was effective in children and adolescents with high-risk B-cell NHL
- Author:
- Mark S. Lesney, PhD
Adding rituximab to chemotherapy was effective in children and adolescents with high-risk, high-grade, mature B-...