Key clinical point: Monocyte-lymphocyte ratio (MLR) was significantly associated with proliferative diabetic retinopathy (PDR) in patients with type 2 diabetes (T2D).
Major finding: Each 0.1 unit increase in MLR increased the risk for PDR by 46% (adjusted odds ratio 1.46; P = .014), with the effects being stable across different subgroups stratified by age, sex, hemoglobin, and glycated hemoglobin categories.
Study details: Findings are from a cross-sectional study of 367 patients with T2D and diabetic retinopathy, of which 27% were diagnosed with PDR.
Disclosures: This study did not receive any funding. The authors declared no conflicts of interest.
Source: Wang H et al. Association of monocyte-lymphocyte ratio and proliferative diabetic retinopathy in the U.S. population with type 2 diabetes. J Transl Med. 2022;20:219 (May 13). Doi: 10.1186/s12967-022-03425-4