VIDEO: Resistant infection risk grows by 1% for each day of hospitalization




WASHINGTON – Length of stay seemed to have the greatest impact on contracting multidrug-resistant strains of gram-negative organisms, with risk maximizing at 10 days of hospitalization. Each day of hospitalization increased the likelihood of contracting an infection with a gram-negative, multidrug-resistant organism by 1%, with risk maximizing at 10 days of hospitalization, said John A. Bosso, Pharm.D.

Researchers led by Dr. Bosso, a professor in the College of Pharmacy at the Medical University of South Carolina, Charleston, analyzed 949 incidents of documented gram-negative infection during 1998-2014. The study is the first to quantify the potential risk of contracting a multidrug-resistant infection based on length of stay.

We caught up with Dr. Bosso, who presented his findings at the annual Interscience Conference on Antimicrobial Agents and Chemotherapy 2014, and asked how health care providers and clinicians can mitigate the risks to patient health. Dr. Bosso said clinicians should be sure to identify which patients are most likely to contract a serious infection, advise patients on the risks associated with long hospital stays, and encourage patients to do their part in getting out of the hospital as quickly as possible.

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