PsA-related uveitis: Real-world data on epidemiology and clinical features

Key clinical point: Uveitis related to psoriatic arthritis (PsA) had a prevalence of approximately 5%, presented as an acute and recurrent disease with anterior and unilateral involvement, and was associated with impaired quality of life and increased functional disability.

Major finding: Uveitis onset was acute in all cases, with 50% being recurrent and 80% being anterior and unilateral. Patients with vs without uveitis had a higher PsA impact of Disease Score (P  =  .001) and Bath Ankylosing Spondylitis Functional Index (P  =  .01) and a higher prevalence of HLA-B27 (P < .0001), sacroiliitis on magnetic resonance imaging (P  =  .027), and ocular surface pathology (P  =  .021).

Study details: This retrospective longitudinal study included 406 patients with PsA, of which 4.9% of patients experienced ≥1 episode of uveitis.

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Disclosures: This study did not receive any specific funding. Several authors declared receiving grants, research support, consulting fees, or honoraria for participation in company-sponsored speaker's bureaus from various sources.

Source: De Vicente Delmás A et al. Uveitis in psoriatic arthritis: Study of 406 patients in a single university center and literature review. RMD Open. 2023;9(1):e002781 (Jan 12). Doi: 10.1136/rmdopen-2022-002781