Instead of the usual eczematous reaction confined to the test area, they exhibited erythema and papules distant from the test area.
In one girl, the reaction consisted of erythematous itchy papules across much of her back on day 2, and by day 4, there were even papules on her chest. In the other girl, erythema, infiltration, and occasional papules covered the whole patch area, and erythematous papules also were seen at some distance from the test area, Nadia Raison-Peyron, MD, of Saint-Eloi Hospital, Montpellier, France, and her colleagues, reported in.
Biopsies were not performed because of the girls’ young age.
SOURCE: Raison-Peyron N et al. Pediatr Dermatol. 2018..