Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Vaginal Preparation Before Cesarean Section

Cochrane Library; ePub 2018 Jul 17; Haas, et al

Vaginal cleansing with povidone-iodine or chlorhexidine solution compared to saline or not cleansing immediately before cesarean delivery likely reduces the risk of post-cesarean endometritis, according to a recent Cochrane review. The review included 11 randomized controlled studies with 3,403 women undergoing cesarean section. The quality of the evidence was moderate for the reported outcomes. Among the findings:

  • Vaginal preparation with antiseptic solution immediately before cesarean delivery likely reduces the incidence of post-cesarean endometritis from 8.7% to 3.8%.
  • Risks of postoperative fever and postoperative wound infection may be slightly lowered by antiseptic preparation.
  • No adverse effects were reported with either the povidone-iodine or chlorhexidine vaginal cleansing.

Citation:

Haas DM, Morgan S, Contreras K, Enders S. Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. Cochrane Database of Systematic Reviews 2018, Issue 7. Art. No.: CD007892. doi:10.1002/14651858.CD007892.pub6.

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